A graph, with annotations added by Insider, showing US hospitalization . Proportion of Adults in the COVID-19Associated Hospitalization Surveillance Network (COVID-NET) Catchment Area and, Figure 2.. Just 35 were fully vaccinated. Booster shots arerecommendedfor most people, as theseincrease and prolongprotection against severe disease and also provide some temporary protection against infection and milder illness. and/or the original MMWR paper copy for printable versions of official text, figures, and tables. The number of observations informing each CI reflects the number of weeks per period: AprilMay (7), June (5), JulyNovember (21), and December (4). Butshe didnt say the agency is not releasing the data anymore, as Kheriaty claimed. doi:10.1101/2022.06.09.22276228 For instance, a Centers for Disease Control and Prevention study. Yet, a March 26 tweet, which went viral, claimed that the CDC is no longer releasing data comparing vaccinated vs unvaccinated deaths & hospitalizations. Even though the tweet was later deleted by its author, it is still being shared on other platforms. Partially vaccinated persons were excluded; reinfections occurring after >90 days were counted as new cases, per current guidance. For primary mRNA vaccination series, the vaccine product of the second dose was used to determine primary series product type. Concern . Beds occupied by non-Covid-19 patients (ICU and Inpatient), which appear in teal. 1:34. But the VE against infection fell from 91.7% to 79.8%. Cookies used to make website functionality more relevant to you. Abbreviations: FDA=Food and Drug Administration; IRR=incidence rate ratio; NC = not calculated for categories with counts <20; NR=not relevant for individual vaccine types because the comparison being made is to overall unvaccinated counts and age-adjusted rates. President Joe Biden visited Somerset County on Tuesday, Sept. 7, 2021, for a meeting with state and county officials in Hillsborough and a tour of storm damage in Manville. Accorsi EK, Britton A, Fleming-Dutra KE, et al. New hospitalizations with laboratory-confirmed COVID-19 among fully vaccinated and unvaccinated adults, vaccine coverage, and estimated vaccine effectiveness, by age New York, May 3-July 25 . Cases have skyrocketed to historic levels. An unvaccinated person had SARS-CoV-2 RNA or antigen detected on a respiratory specimen and has not been verified to have received COVID-19 vaccine. The report did say that 83.7% of Covid patients admitted to hospital were unvaccinatedbut this covered the period between 8 December 2020, when vaccination started . Summary. At his weekly pandemic briefing on Monday, Gov. Fully vaccinated persons were those with a completed primary series of 2 doses of the Pfizer-BioNTech or Moderna mRNA vaccine or a single dose of the Janssen vaccine (https://www.cdc.gov/coronavirus/2019-ncov/vaccines/stay-up-to-date.html). You can also edit metadata from this page. The C.D.C. COVID-19 Incidence and Death Rates Among Unvaccinated and Fully Vaccinated Adults with and Without Booster Doses During Periods of Delta and Omicron Variant Emergence 25 U.S. Jurisdictions, April 4December 25, 2021. CDC COVID-19 Response Team. Rates of COVID-19 deaths by vaccination status are reported based on when the patient was tested for COVID-19, not the date they died. According to this data, for example, unvaccinated people over 5 years old were 2.4 times more likely to test positive for COVID-19 and 9 times more likely to die from COVID-19 in January. Suggested citation for this article: Johnson AG, Amin AB, Ali AR, et al. Persichilli has said that the bulk of COVID patients in the state's hospitals about 70% are unvaccinated. Since the vaccine rollout began last December, less than one third of 1% of fully vaccinated Garden State residents have tested positive for COVID, and of the more than 5 million people fully . New Jersey officials called for federal reinforcements to make up for depletion in hospital staff as the virus continues to infect more of them. , * Events per 100,000 population. The headline of a blog post, published on June 23 by DC Clothesline, reads: "Vaccinated people found to be 600% more likely to die from covid "variants" than unvaccinated people" (archive . 33.6% were "under-vaccinated," meaning they either received only one shot of the Pfizer or Moderna vaccine, or have not received a booster shot. They were eight times more likely to be hospitalized with COVID-19 than fully vaccinated people without a booster. Accessed 1 Apr 2022. A spokesperson for the CDC told the New York Times a few weeks ago, the reason that they are not releasing the data anymore, that weve seen throughout the pandemic, is they have worries its not ready for prime time because it might increase vaccine hesitancy. What are the implications for public health practice? ** 95% CIs were calculated after detrending underlying linear changes in weekly incidence rates using piecewise linear regression. The new data, published in the U.S . On September 24, 2021, CDC recommended a Pfizer-BioNTech booster dose for certain Pfizer-BioNTech primary series recipients, including all adults aged 65 years and persons aged 18 years in certain populations and high risk occupational and institutional settings. The C.D.C. This analysis represents the combined impact of BNT162b2 (Pfizer-BioNTech), mRNA-1273 (Moderna), and Ad.26.COV2.S (Janssen [Johnson & Johnson]) COVID-19 vaccines, which had different clinical efficacies against confirmed infection; fully vaccinated persons also include those persons who received additional primary doses and booster doses starting in mid-August. Fewer than 0.5% of COVID-19 deaths across all ages in 2022 have been among people under 25. If the Janssen vaccine was either the first dose or the second dose, the series type was called Janssen. Mbaeyi S, Oliver SE, Collins JP, et al. Between August 12, 2021, and December 6, 2021, 10,236 ED encounters with a primary diagnosis of COVID-19 were observed. Younger Americans Benefited Less From Booster Shots Than Older People. The New York Times. Rates of laboratory-confirmed COVID-19 hospitalizations by vaccination status. Understanding risk factors for hospitalization in vaccinated persons and the association of COVID-19 vaccines with hospitalization rates is critical for public health efforts to control COVID-19. The state continues to see long lines at clinics, few rapid tests available on pharmacy shelvesand longer turnaround times for results. The next update for rates of cases and deaths by vaccination status will be mid-April and include case data through mid-March and death data through late February. The share of hospitalizations among those with COVID-19 who are not fully vaccinated ranged from in 95.02% in Alaska to 99.93% in New Jersey. In an email sent to FactCheck.org on March 28, Morefield said he decided to remove his tweet after admitting that the CDC does release some -though not all or enough- data on an agency website. Washington Offices and Barbara Jordan Conference Center: 1330 G Street, NW, Washington, DC 20005 | Phone 202-347-5270, www.kff.org | Email Alerts: kff.org/email | facebook.com/KaiserFamilyFoundation | twitter.com/kff. MMWR Morb Mortal Wkly Rep. 2021;70(37):1294-1299. doi:10.15585/mmwr.mm7037e3 It would be a misrepresentation of the finding to say it is evidence against vaccination. Since the vaccine rollout began last December, less than one third of 1% of fully vaccinated Garden State residents have tested positive for COVID, and of the more than 5 million people fully vaccinated by the end of August, a total of 386 have been hospitalized. ** Reporting is by primary series vaccine type rather than additional or booster dose vaccine type. Peaks in age-standardized case and death rates occurred during August (>95% of infections attributed to the Delta variant); case rates also peaked during the 2 weeks ending December 18 and 25 (39% and 72% infections attributed to the Omicron variant, respectively) (Figure). Average weekly, age-standardized rates of cases and deaths (events per 100,000 population) were higher during periods of Delta predominance and Omicron emergence than during pre-Delta and Delta emergence periods and were consistently higher in all periods among unvaccinated persons (range=64.0725.6 [cases] and 1.511.4 [deaths]) than among fully vaccinated persons (range=7.4230.9 and 0.10.7). New Jersey announced 25,277 new cases confirmed by PCR tests Tuesday, the seventh straight day with more than 20,000 new infections, and another 5,137 confirmed through antigen tests. The share of COVID-19 deaths among those who are vaccinated has risen. Per national guidance, this should include persons whose death certificate lists COVID-19 disease or SARS-CoV-2 as an underlying cause of death or as a significant condition contributing to death. On October 21, 2021, CDC recommended a booster dose for adults aged 18 years who had received the Janssen vaccine and for Pfizer-BioNTech or Moderna primary series vaccine recipients, including all adults aged 65 years and persons aged 18 years in certain populations and high risk occupational and institutional settings (https://www.cdc.gov/media/releases/2021/p1021-covid-booster.html). The goal of the project is to increase exposure to accurate information about COVID-19 and vaccines, while decreasing the impact of misinformation. The booster dose vaccine type may be different than the primary series vaccine type. To interpret IRR changes, age-standardized crude vaccine effectiveness (VE) was estimated as (1 [incidence in vaccinated / incidence in unvaccinated]). This analysis represents the combined impact of the Pfizer-BioNTech, Moderna, and Janssen COVID-19 vaccines, which had different clinical efficacies against confirmed infection. Rates of COVID-19 Cases and Deaths by Vaccination Status. that during the omicron wave, adults who had received two doses of the Pfizer/BioNTech or Moderna vaccines had a 79% lower risk of dying or needing a ventilator if hospitalized with COVID-19, compared with unvaccinated adults. Excluded were partially vaccinated people who received at least one FDA-authorized vaccine dose but did not complete a primary series 14 days before collection of a specimen where SARS-CoV-2 RNA . People who were partially vaccinated are not included in this data. Fourth, variable data linkage completeness might have resulted in misclassifications (e.g., booster doses not being linked to primary series) that could influence IRR estimates (5). -, Butt AA, Talisa VB, Shaikh OS, Omer SB, Mayr FB. Breakthrough infection and hospitalization data vs. the unvaccinated on a rolling basis per 100K New York residents Ultimately, there's no sugarcoating any component of the numbers right now . Health department officials have not said where the extra staffers will be deployed. The CDC data show that about 95% of adults who died from COVID-19 in 2022 in these jurisdictions were over age 50, and about 8 in 10 were age 65 or older, underscoring the need for older adults to stay up-to-date on recommended booster shots. COVID hospitalization in NJ reach 8-month high. Against omicron, however, the vaccines havent. Average weekly incidences and rate ratios are provided by age group, primary series vaccine type, and overall; overall and vaccine-specific rates were standardized by age, according to the enumerated 2000 U.S. Census age distribution. A large majority of new hospitalizations and deaths from COVID-19 are occurring among unvaccinated people. The agency has not communicated any intention to discontinue these publications. MMWR Morb Mortal Wkly Rep. 2021;70(44):1545-1552. doi:10.15585/mmwr.mm7044e2 "A majority of these cases are in unvaccinated individuals." Data shows the province administered 48,000 vaccines through Monday, 38,000 of which were second shots and 10,416 were first doses. Those who had received a booster vaccine dose as well had a 94% lower risk. The CDC monitors rates of COVID-19 cases and deaths and laboratory-confirmed COVID-19 hospitalizations by vaccination status and age group, and publishes data and interactive tables on its website monthly, where anyone can download them. During OctoberNovember, unvaccinated persons had 13.9 and 53.2 times the risks for infection and COVID-19associated death, respectively, compared with fully vaccinated persons who received booster doses, and 4.0 and 12.7 times the risks compared with fully vaccinated persons without booster doses. SARS-CoV-2 RNA Levels in Wastewater in the United States. https://www.medrxiv.org/content/10.1101/2022.01.07.22268919v1.full; https://papers.ssrn.com/sol3/papers.cfm?abstract_id=4011905. Hospitalization was significantly linked with a lower likelihood of vaccination, with 15.8% of infected patients and 54.8% of controls, including for the . In order to be counted as vaccinated, a person must be at least two weeks out from completing their primary series before testing positive (for example, at least 14 days after completing two doses of the mRNA vaccine). Thank you for taking the time to confirm your preferences. Stupica D, Collinet-Adler S, Kejar N, Poljak M, tamol T. J Clin Med. Data from 41 states are now available. Data from the Centers for . Indeed, vaccinated people now make up the majority of the population 79% of adults have completed at least the primary series and the latest CDC data show that vaccinated people also now represent the majority of COVID-19 deaths. "If we don't have the medical staff to go out there and take care of patients, it's really going to be all for naught," Callahan said Monday. This change requires a reload. Balian S, Bailey B, Abboud S, Kim Y, Humphries D, Kambali S, Kalangi ST, Jarvis J, Dayal L, Beiz H, Battisti R, Haddad N. J Investig Med. * A COVID-19 case in a fully vaccinated person occurred when SARS-CoV-2 RNA or antigen was detected in a respiratory specimen collected 14 days after completing the primary series of a COVID-19 vaccine with FDA approval or emergency use authorization. of pages found at these sites. Krutika Amin Follow @KrutikaAmin on Twitter COVID-19 vaccines reduced risks for SARS-CoV-2 infection and COVID-19associated death during periods of Delta variant predominance and infection risk during Omicron variant emergence. All HTML versions of MMWR articles are generated from final proofs through an automated process. They are, for the most part, unvaccinated, or vaccinated but . The claim: Death rate among COVID-19 vaccinated people is significantly higher compared with unvaccinated population. The https:// ensures that you are connecting to the The surge in hospitalizations is projected to peak between 6,000 and 9,000 later this month and is being driven in part by the spread of the omicron variant. -, Bajema KL, Dahl RM, Prill MM, et al. MMWR Morb Mortal Wkly Rep. 2022 Jan 28;71(4):125-131. doi: 10.15585/mmwr.mm7104e1. Fericean RM, Oancea C, Reddyreddy AR, Rosca O, Bratosin F, Bloanca V, Citu C, Alambaram S, Vasamsetti NG, Dumitru C. Int J Environ Res Public Health. A spokesperson for the CDC, Kristen Nordlund, told the New York Times the agency has been slow to release some data because its not ready for prime time and because of the fear that it could be misinterpreted. Online ahead of print. *** 45 C.F.R. MMWR Morb Mortal Wkly Rep 2022;71:132138. In an email sent to FactCheck.org on March 28, Morefield said he decided to remove his tweet after admitting that the CDC does release some -though not all or enough- data on an agency, Clinical Trials Find No Increase in Mortality Among COVID-19 Patients Treated with Remdesivir, Contrary to Viral Claim, Rates of COVID-19 Cases and Deaths by Vaccination Status, Rates of laboratory-confirmed COVID-19 hospitalizations by vaccination status, SARS-CoV-2 RNA Levels in Wastewater in the United States. Len TM, Dorabawila V, Nelson L, Lutterloh E, Bauer UE, Backenson B, Bassett MT, Henry H, Bregman B, Midgley CM, Myers JF, Plumb ID, Reese HE, Zhao R, Briggs-Hagen M, Hoefer D, Watt JP, Silk BJ, Jain S, Rosenberg ES. Age-standardized IRRs for deaths among unvaccinated versus fully vaccinated persons were relatively stable; crude VE for deaths was 95% during AprilMay, 94% during June, and 94% during JulyNovember. 31 Mar 2022. Respondent demographic characteristics by HPV vaccination vs. intent status. This site needs JavaScript to work properly. Sect. When the Omicron variant emerged during December 2021, case IRRs decreased to 4.9 for fully vaccinated persons with booster doses and 2.8 for those without booster doses, relative to OctoberNovember 2021. Exposures: COVID-19-Associated Hospitalizations Among Adults During SARS-CoV-2 Delta and Omicron Variant Predominance, by Race/Ethnicity and Vaccination Status - COVID-NET, 14 States, July 2021-January 2022. Weekly rates of COVID-19 hospitalizations and deaths by vaccination status are published monthly by the Centers for Disease Control and Prevention on its website. Published online May 3, 2022. HHS Vulnerability Disclosure, Help 3rd ed. Rates of COVID-19 deaths by vaccination status are reported based on when the patient was tested for COVID-19, not the date they died. Paz-Bailey G, Sternberg M, Kugeler K, et al. https://www.cdc.gov/coronavirus/2019-ncov/vaccines/different-vaccines.html. New variants combined with a reduction in masking and other non-pharmaceutical interventions may also lead to more transmission, which can in turn lead to more deaths. High Intent mothers had younger children overall than Already Vaccinated mothers (41.9% of High Intent vs. 18.2% of Already Vaccinated had an 11-year-old child, p<0.001). analysis posted on the Peterson-KFF Health System Tracker, unvaccinated people are at much greater risk of death, 14% of adults overall and 31% of older adults (65 years and older) have received the latest bivalent boosters. The state is asking FEMA to send strike forces to bolster hospital staff and National Guard to help depleted nursing home staff as COVID spikes. Relative vaccine effectiveness of a SARS-CoV-2 mRNA vaccine booster dose against the Omicron variant. An additional factor to consider is that as the pandemic wears on and a disproportionate number of unvaccinated people . Question Do individuals fully vaccinated against COVID-19 have a shorter duration of viable SARS-CoV-2 viral shedding and a lower rate of secondary transmission than in partially vaccinated or unvaccinated individuals?. Last updated 31 Mar 2022. Saving Lives, Protecting People, Association Between 3 Doses of mRNA COVID-19 Vaccine and Symptomatic Infection Caused by the SARS-CoV-2 Omicron and Delta Variants, https://ndc.services.cdc.gov/case-definitions/coronavirus-disease-2019-2021/, https://www.cdc.gov/coronavirus/2019-ncov/vaccines/stay-up-to-date.html, https://www.cdc.gov/coronavirus/2019-ncov/vaccines/different-vaccines.html, https://www.cdc.gov/media/releases/2021/s0813-additional-mRNA-mrna-dose.html, https://www.cdc.gov/media/releases/2021/p0924-booster-recommendations-.html, https://www.cdc.gov/media/releases/2021/p1021-covid-booster.html, https://www.cdc.gov/media/releases/2021/s1119-booster-shots.html, https://www.cdc.gov/media/releases/2021/s1129-booster-recommendations.html, https://cdn.ymaws.com/www.cste.org/resource/resmgr/pdfs/pdfs2/20211222_interim-guidance.pdf, https://covid.cdc.gov/covid-data-tracker/#variant-proportions, https://www.census.gov/programs-surveys/popest/data/tables.2019.html, https://www.cdc.gov/nchs/data/statnt/statnt20.pdf, https://www.medrxiv.org/content/10.1101/2022.01.07.22268919v1.full, https://papers.ssrn.com/sol3/papers.cfm?abstract_id=4011905, https://covid.cdc.gov/covid-data-tracker/#rates-by-vaccine-status, https://covid.cdc.gov/covid-data-tracker/#covidnet-hospitalizations-vaccination, https://doi.org/10.1146/annurev-ecolsys-112414-054242, https://www.cdc.gov/nchs/data/statnt/statnt24.pdf, Centers for Disease Control and Prevention, U.S. Department of Health & Human Services, Omicron emergence (first week in December 2021). Atlanta, GA: US Department of Health and Human Services, CDC; 2021. Itcomes at a time of staff shortages during what is traditionally a hospital's busiest time of year with seasonal ailments from the flu which is particularly bad this year to injuries such asslipping on ice. Key Points. In particular, the story said the CDC left out data on the effectiveness of boosters in people ages 18 to 49. Please choose whether or not you wish to save this view before you leave; or choose Cancel to return to the page. The site is secure. Open in External Program. 4 Feb 2022. She has askedfor a FEMA strike force to be deployed at depleted hospitals and the National Guard to fill in at nursing homes where almost 6,000 staffers have recently tested positive. Accessed May 15, 2022. New Jersey's testing sites have been strained for weeks before, during and after the holidays. The data also shows during that same week, 945 people were hospitalized. Views equals page views plus PDF downloads. Concern about omicron among the unvaccinated dropped from 52% to 44% between December 24 and 30, the Morning Consult poll found, which was conducted among 2,220 U.S. adults. In this cross-sectional study of US adults hospitalized with COVID-19, unvaccinated adults were more likely to be hospitalized compared with vaccinated adults; hospitalization rates were lowest in those who had received a booster dose. COVID-19-associated hospitalization rates among vaccinated vs unvaccinated persons and factors associated with COVID-19-associated hospitalization in vaccinated persons were assessed. The data on COVID-19 hospitalizations are collected by COVID-NET, a surveillance system that collects data on hospitalizations of children and adults with a confirmed infection through a network of over 250 hospitals in 14 states. Even with these reviews, it may sometimes be hard to determine the primary cause of death for someone with significant underlying health conditions, though these data are intended to be limited to cases where COVID-19 was a significant contributor to the death. Average weekly incidence rates and rate ratios are provided by age group, primary series vaccine type, and overall; overall and vaccine-specific rates were standardized by age, according to the enumerated 2000 U.S. Census age distribution. The COVID-19 case and death rate data by vaccination status were last updated on March 17, and cover April 2021 to Feb. 19 for cases and through Jan. 29 for deaths. COVID-19 vaccines are highly effective at preventing severe disease, hospitalization, and death [] The death data were last posted on March 17, and the hospitalization data on March 31. Rates of COVID-19 deaths by vaccination status are reported based on when the patient was tested for COVID-19, not the date the patient died. Arthur Presnetsov, Adam Schiller, Vaccine Task Force, CDC COVID-19 Emergency Response Team. Claudia Corwin, MD, MPH, an occupational medicine specialist and associate director of the University Employee Health Clinic, breaks down the biggest differences between delta variant COVID-19 infection in vaccinated and unvaccinated people. More transmission can also lead to more deaths. government site. In an analysis, the Post found that if vaccinated people are removed from assessing the data, the case rate for unvaccinated Americans is similar to the case rate for all residents on December 31. Data for CDCs COVID Data Tracker site on Rates of COVID-19 Cases and Deaths by Vaccination Status. A, A spokesperson for the CDC, Kristen Nordlund, told the. Variant proportions. adds wastewater data to its Covid-19 tracker. The numbers are over the past 30 days: Scott Fallon has covered the COVID-19 pandemic since its onset in March 2020. Federal government websites often end in .gov or .mil. This decline suggests a change in crude VE for infection from 93% during AprilMay, to 89% during June, 80% during JulyNovember, and to 68% during December. COVID-19 Cases and Hospitalizations by COVID-19 Vaccination Status and Previous COVID-19 Diagnosis - California and New York, May-November 2021. * Events per 100,000 population. Centers for Disease Control and Prevention, COVID-19 Response. Weekly VE against infection dropped in . Comparative admission rates and infection severity of COVID-19 among unvaccinated and vaccinated patients. A COVID-19 case in a fully vaccinated person with a booster dose occurred when a person had SARS-CoV-2 RNA or antigen detected on a respiratory specimen collected 14 days after receipt of at least 1 additional or booster dose of any COVID-19 vaccine on or after August 13, 2021 (this definition does not distinguish between vaccine recipients who are immunocompromised and are receiving an additional dose versus those who are not immunocompromised and receiving a booster dose). By this far into the pandemic, it is estimated that many unvaccinated people have had COVID-19 at least once and while hundreds of thousands of unvaccinated people have needlessly died from COVID, those who survived may have gained some immune protection against the virus that can help protect them against severe outcomes when they have subsequent infections. (Note: Hospitalization may or may not have been due to . Phil Murphy said from August 23-29 a total of 12,051 people tested positive for the virus in the Garden State, and 2,603 of them were fully vaccinated. ** A COVID-19associated death occurred in a person with a documented COVID-19 diagnosis who died, and whose report local health authorities reviewed (e.g., using vital records, public health investigation, or other data sources) to make that determination. NJ seeks reinforcements to help hospital staff depleted by COVID. Reed, Jasmine. Throughout the pandemic, each spike in cases has taken its toll on hospital systems, and the omicron surge has been no . * These authors contributed equally to this report. Epub December 20, 2021. Now we have all the information we need and can calculate the death rates:. Hospitalizations had peakedat 8,270on April 15, 2020. Hospitalizations have quadrupled in one month from early December and intensive care admissions and ventilator use have each tripled in that time. Ascertaining vaccination status for COVID-19 patients through active linkage of case surveillance and immunization information systems typically assumes that cases among persons who are unmatched to the registry are unvaccinated. National weighted estimates of the proportions of infections attributed to SARS-CoV-2 variants by week are based on analyses of whole-genome sequencing results submitted to or performed by CDC (https://covid.cdc.gov/covid-data-tracker/#variant-proportions). DOI: http://dx.doi.org/10.15585/mmwr.mm7104e2. Alabama, Arkansas, California, Colorado, District of Columbia, Florida, Georgia, Idaho, Indiana, Kansas, Louisiana, Massachusetts, Michigan, Minnesota, Nebraska, New Jersey, New Mexico, New York, New York City (New York), Rhode Island, Seattle/King County (Washington), Tennessee, Texas, Utah, and Wisconsin. Weekly / January 28, 2022 / 71(4);132138. Outcomes of Elderly Patients Hospitalized with the SARS-CoV-2 Omicron B.1.1.529 Variant: A Systematic Review. This finding actually underscores the importance of staying up-to-date on boosters. Email sent to FactCheck.org. Mandavilli, Apoorva. Josh Michaud Follow @joshmich on Twitter Editors note:SciChecks COVID-19/Vaccination Projectis made possible by a grant from the Robert Wood Johnson Foundation. SARS-CoV-2 B.1.1.529 (Omicron) variantUnited States, December 18, 2021. The COVID-19 case definition, including criteria to distinguish a new case from an existing case, is per the July 2021 update to the national standardized surveillance case definition and national notification for 2019 novel coronavirus disease (COVID-19) (21-ID-01) (https://ndc.services.cdc.gov/case-definitions/coronavirus-disease-2019-2021/). -. During OctoberNovember, age-standardized IRRs for deaths among unvaccinated persons were 53.2 compared with those in fully vaccinated persons with a booster dose and 12.7 compared with persons without a booster dose; these results represented crude VE against death of 98% and 92%, respectively. Similarly, as the share of the population with a booster rose somewhat during 2022, the share of deaths among boosted people also rose. The waning protection from vaccines is why CDC recommends recent booster shots, and why its especially important for people at higher risk to stay up-to-date on boosters. Eligible persons should stay up to date with COVID-19 vaccinations. SAS (version 9.4; SAS Institute) and R (version 4.1.0; R Foundation) were used to conduct all analyses. All of the authorized and approved vaccines are effective at preventing severe COVID-19.